Well the buttons themselves, and the minimap, is from an addon called Bongos2 - I just placed the buttons individually until I hit a design I like. I got one of those "natural" keyboards that is split in the middle so I decided to devide the buttons in half aswell, devided by the minimap.
The button layout is mirrored on each side. Basicly I have the main bar, thats the one in the middle of the 3 rows, 6 buttons and the only "straight" hotbar - hot-keyed by 1 -> 6
Then it was just a matter of placing the other buttons around that, put 4 above hot-keyed F1 -> f4, and some below hot-keyed ALT+1 -> ALT+6
Combat essential buttons in the left and others on the right, most of the rightsider is not hotkeyed so I mouse-click those.
Note that a setup like this only works if you know what buttons are hotkeyed where since the button-layout isnt that logical. Eg I have my feign death hotkeyed to the (1/2 key, the one just above TAB) for very easy access, but the button itself is located on the left side at the top.
Oof long describtion, prolly a lot confusing or whatnot, feel free to ask here or ingame if there is anything particualr you want to know.
Bongos2: http://www.wowinterface.com/downloads/info4744-Bongos2.html
/Brum